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决-44 Uniportal VATS Left Upper Double Sleeve Lobectomy

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Clinical Case Summary 1. The patient is a 67-year-old male who presented with a one-month history of productive cough and recurrent fever. 2. Computed tomography (CT) revealed occlusion of the left upper lobe bronchus with consequent lobar collapse. 3. Bronchoscopy identified substantial white necrotic material obstructing the left upper lobe orifice. Upon suction and removal, an underlying neoplasm causing near-total luminal occlusion was visualized, followed by a copious outflow of white purulent secretion. 4. Endoscopic biopsy confirmed the diagnosis of moderately differentiated squamous cell carcinoma, with a PD-L1 Tumor Proportion Score (TPS) of 10%. 5. Staging evaluations via PET-CT and brain MRI demonstrated no evidence of lymph node or distant metastasis, establishing a clinical stage of cT2aN0M0. 6. Following a multidisciplinary discussion and patient consultation, three cycles of neoadjuvant immuno-chemotherapy were administered. Subsequent preoperative imaging assessment indicated a partial response (PR). 7. The patient subsequently underwent a uniportal video-assisted thoracoscopic surgery (VATS) left upper double sleeve lobectomy with systemic lymphadenectomy. 8. The postoperative course was uneventful. The chest tube was removed on postoperative day 3, and the patient was discharged on day 4. Final pathological examination of the resected specimen confirmed a pathological complete response (pCR). 9. At the 2-week follow-up, the patient was recovering well and reported no specific complaints.

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