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G11 MIE(McKeown) after Neoadjuvant Immunotherapy and Chemotherapy

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患者,男性,59岁,主因吞咽困难2个月入院。胃镜示:食管距门齿30-35cm可见溃疡型新生物。病理:鳞癌。CT示:1.食管胸中下段管壁增厚,符合食管癌表现。2.右侧气管旁沟增大淋巴结。 超声胃镜分期示:T3N1。双锁骨上超声提示未见肿大淋巴结。临床分期cT3N1M0。 基线检查无禁忌,给予新辅助免疫治疗联合化疗2个周期。新辅助治疗后临床分期cT0NxM0。新辅助治疗5周后行全腔镜McKeown手术,术中彻底清扫左右喉返神经旁、隆突、食管旁、胃左、贲门旁等胸腹腔区域淋巴结。手术顺利,术中共清扫淋巴结72枚。术后恢复顺利,术后第9天出院。 术后病理:食管处可见一个1.5cmx1.0cm黏膜粗糙区。瘤床处未见残余癌[CAP/NCCN(Ryan)分级0级]。环周切缘(-)。临床上残(-)下残(-)。淋巴结:1/72转移。 术后病理分期:ypT0N1M0(ⅢA) 术后给予免疫单抗维持治疗,随访无复发。

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